The field of research on psychedelics’ effect on substance use disorder is growing. A study published in October of 2022 on treating alcohol use disorder with psilocybin suggests that psilocybin could facilitate lasting behavior changes for individuals suffering from substance use disorder. Dr. Jeffrey Guss, a Lead Trainer at Fluence and a therapist supporting lead investigators for that study, witnessed study participants feeling the negative consequences of their drinking “at a very deep level.”